HDT Quickguide

Formålet er at give et overblik over fremgangsmåden, vejledninger samt procedurer indeholdt i et indlæggelsesforløb for patienter, der behandles med højdosis kemoterapi med autolog stamcellestøtte.

Dette er en afkortet udgave af forløbet med højdosis kemoterapi med stamcellestøtte. Vil du vide mere kan du finde en uddybende beskrivelse på dansk hæmatologisk hjemmeside:

Rekommandationer for stamcellemobilisering/høst og højdosis kemoterapi med autolog stamcelletransplantation hos voksne

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Læger, sygeplejersker, diætister og fysioterapeuter i Afdeling for Blodsygdomme. 

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HDT: højdosis kemoterapi med autolog stamcellestøtte.

CTCAE: Common Terminology Criteria for Adverse Events

WHO: World Health Organisation

NRS: Numerisk Rang Scala

AOP: Anamnese – Objektivt - Plan

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De sygeplejefaglige observationer og handlinger beskrevet i nedenstående tabel skal dokumenteres i SP-vurderingsskema ”HDT dagligvurdering” x 2 dagligt.

HDT quickguide.pdf

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Teamledelsen, Team 1

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1. S A Giralt, K F Mangan, R T Maziarz, J S Bubalo, R Beveridge, … D D Hurd, F L Mendoza, E B Rubenstein, T J DeGroot, M W Schuster: Three palonosetron regimens to prevent CINV in myeloma patients receiving multiple-day high-dose melphalan and hematopoietic stem cell transplantation. Annals of oncology official journal of the European Society for Medical Oncology ESMO (2011) Volume: 22, Issue: 4, Pages: 939-946
2. W. Pielichowski, JBarzal, K. Gawronski, B. Mlot, S. Oborska, A. Wasko-Grabowska, P. Rzepecki: A triple-drug combination to prevent nausea and vomiting following BEAM chemotherapy before autologous hematopoietic stem cell transplantation; Transplantation Proceedings, 43, 2011, 3107-3110
3. Hong CHL, Gueiros LA, Fulton JS, et al. Systematic review of basic oral care for the management of oral mucositis in cancer patients and clinical practice guidelines. Support Care Cancer. 2019;27(10):3949-3967. doi:10.1007/s00520-019-04848-4
4. Bowen JM, Gibson RJ, Coller JK, et al. Systematic review of agents for the management of cancer treatment-related gastrointestinal mucositis and clinical practice guidelines. Support Care Cancer. 2019;27(10):4011-4022. doi:10.1007/s00520-019-04892-0
5. Ariyawardana A, Cheng KKF, Kandwal A, et al. Systematic review of anti-inflammatory agents for the management of oral mucositis in cancer patients and clinical practice guidelines. Support Care Cancer. 2019;27(10):3985-3995. doi:10.1007/s00520-019-04888-w
6. Muehlbauer PM, Thorpe D, Davis A, Drabot R, Rawlings BL, Kiker E;  Putting Evidence Into Practice: Evidence-Based Interventions to Prevent, Manage, and Treat Chemotherapy- and Radiotherapy-Induced Diarrhea; Clinical Journal of Oncology Nursing; Volume 13, Number 3, 336-341
7. McGuire DB et al. Systematic review of basic oral care for the management of oral mucositis in cancer patients. Support Care Cancer 2013;21: 3165-3177
8. WHO Oral Toxicity Scale WHO: http://www.who.int/en/
9. Jann Arends et al,: ESPEN guidelines on nutrition in cancer patients, 2016Jarden M, Baadsgaard MT, Hovgaard DJ. A randomized trial on the effect of a multimodal intervention on physical capacity, functional performance and quality of life in adult patients undergoing allogeneic SCT. Bone Marrow Transplantation, 2009;43: 725-737.
10. Baumann FT et al. Physical activity for patients undergoing an allogeneic hematopoietic stem cell transplantation: benefits of a moderate exercise intervention. Eur J Haematol, 2011; 87(2):14.

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